Map of DNA homology between the genomes of Salmonella bacteriophages P22 and L.
نویسندگان
چکیده
The genomes of temperate Salmonella typhimurium phages P22 and L share approximately 69% homology, as measured by DNA heteroduplex analysis. Alignment of the P22/L heteroduplex molecules with a P22 physical map places most of this homology between the capsid genes and genes in the vicinity of the prophage attachment sites. The degree of genetic relatedness between these phages and the lambdoid phages is also discussed.
منابع مشابه
Genomics of Three New Bacteriophages Useful in the Biocontrol of Salmonella
Non-typhoid Salmonella is the principal pathogen related to food-borne diseases throughout the world. Widespread antibiotic resistance has adversely affected human health and has encouraged the search for alternative antimicrobial agents. The advances in bacteriophage therapy highlight their use in controlling a broad spectrum of food-borne pathogens. One requirement for the use of bacteriophag...
متن کاملSelection of polyvalent bacteriophages infecting Salmonella enterica serovar Choleraesuis
Article history: Received 24 September 2015 Accepted 22 January 2016 Available online 7 April 2016 Background: Ideally, bacteriophages of pathogenic bacterial hosts should be polyvalent to be able to replicate in an alternative nonpathogenic bacterium. Thus, accidental infection by the original host can be avoided when bacteriophage lysates are used in biocontrol protocols. Results: From 15 was...
متن کاملA physical gene map of the bacteriophage P22 late region: genetic analysis of cloned fragments of P22 DNA.
A physical gene map of the late region of the P22 chromosome has been constructed by genetic analysis of restriction enzyme fragments of P22 DNA cloned in a plasmid vector. Cleavage sites for restriction endonucleases SalI, SstI, SmaI, XhoI, and BglI were mapped on P22 DNA to provide physical reference points in addition to the EcoRI, HindIII, and BamHI cleavage sites previously mapped. Restric...
متن کاملDetection of activating enzymes for 4-nitroquinoline 1-oxide activation with a microbial assay system.
4-Nitroquinoline 1-oxide (4NQO) damages bacterial genomes but not phage genomes. A reduction product of 4NQO, 4-hydroxyaminoquinoline 1-oxide (4HAQO), damages both the bacterial and phage genomes. These results imply that Salmonella typhimurium is able to convert 4NQO to 4HAQO and that 4HAQO reacts with the genomes. When phage P22 is treated with 4HAQO and assayed on S. typhimurium strains lyso...
متن کاملApplication of bacteriophages to control Salmonella Enteritidis in raw eggs
Background: Salmonella, a bacterial genus of more than 2500 serotypes is considered as the most significant foodborne pathogen causing infections in humans and animals. Increased antimicrobial resistance and persistence of antimicrobial residues in food matrices warrants the need for alternative infection management strategies. Aims: The present study aimed to isolate and evaluate the lytic act...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of virology
دوره 56 3 شماره
صفحات -
تاریخ انتشار 1985